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Article

Independent strong association of HLA-A02:06 and HLA-B44:03 with cold medicine-related Stevens-Johnson syndrome with severe mucosal involvement

30 Apr 2014

Abstract excerpt

Stevens-Johnson syndrome (SJS) and its severe variant, toxic epidermal necrolysis (TEN), are acute inflammatory vesiculobullous reactions of the skin and mucous membranes. Cold medicines including non-steroidal anti-inflammatory drugs (NSAIDs) and multi-ingredient cold medications are reported to be important inciting drugs. We used two sample sets of Japanese patients to investigate the association between HLA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 24781922
DOI: 10.1038/srep04862

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Independent strong association of HLA-A*02:06 and HLA-B*44:03 with cold medicine-related Stevens-Johnson syndrome with severe mucosal involvementPMID 24781922Read ↗

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