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Article

Human Leukocyte Antigen Class I Genes Associated With Stevens-Johnson Syndrome and Severe Ocular Complications Following Use of Cold Medicine in a Brazilian Population.

JAMA ophthalmology - 1 Apr 2017

Wakamatsu Tais H, Ueta Mayumi, Tokunaga Katsushi, Okada Yukinori, Loureiro Renata R, Costa Karita A, Sallum Juliana Maria F, Milhomens José Arthur, Inoue Chikara, Sotozono Chie, Gomes José Álvaro P, Kinoshita Shigeru

Abstract excerpt

Importance: Describing the association with human leukocyte antigen (HLA) alleles could facilitate the understanding of increased risk factors for development of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) in patients with severe ocular complications (SOCs). Objective: To investigate the association between HLA class I genes and cold medicine (CM)-associated SJS/TEN with SOCs. Design,...

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Identifiers

PMID: 28278336
DOI: 10.1001/jamaophthalmol.2017.0074
PMCID: PMC5470496

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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