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Article

HLA genotypes and cold medicine-induced Stevens-Johnson syndrome/toxic epidermal necrolysis with severe ocular complications: a systematic review and meta-analysis.

Scientific reports - 29 Jun 2020

Tangamornsuksan Wimonchat, Chanprasert Sirikan, Nadee Phenphechaya, Rungruang Saowalak, Meesilsat Natnaree, Ueta Mayumi, Lohitnavy Manupat

Abstract excerpt

Serious cutaneous adverse drug reactions [i.e., SJS/TEN with severe ocular complications (SOC)] associated with cold medicine (CM) were reported in several studies. To assess the risks of CM-induced SJS/TEN with SOC, systematic review and meta-analysis were employed. Studies investigating associations between HLA genotypes and CM-induced SJS/TEN with SOC were systematically searched in PubMed, Scopus and the...

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Identifiers

PMID: 32601360
DOI: 10.1038/s41598-020-67610-5
PMCID: PMC7324363

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