IKZF1, a new susceptibility gene for cold medicine-related Stevens-Johnson syndrome/toxic epidermal necrolysis with severe mucosal involvement.

doi:10.1016/j.jaci.2014.12.1916

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

IKZF1, a new susceptibility gene for cold medicine-related Stevens-Johnson syndrome/toxic epidermal necrolysis with severe mucosal involvement.

The Journal of allergy and clinical immunology - 1 Jun 2015

Ueta Mayumi, Sawai Hiromi, Sotozono Chie, Hitomi Yuki, Kaniwa Nahoko, Kim Mee Kum, Seo Kyoung Yul, Yoon Kyung-Chul, Joo Choun-Ki, Kannabiran Chitra, Wakamatsu Tais Hitomi, Sangwan Virender, Rathi Varsha, Basu Sayan, Ozeki Takeshi, Mushiroda Taisei, Sugiyama Emiko, Maekawa Keiko, Nakamura Ryosuke, Aihara Michiko, Matsunaga Kayoko, Sekine Akihiro, Gomes José Álvaro Pereira, Hamuro Junji, Saito Yoshiro, Kubo Michiaki, Kinoshita Shigeru, Tokunaga Katsushi

Abstract excerpt

BACKGROUND: Stevens-Johnson syndrome (SJS) and its severe form, toxic epidermal necrolysis (TEN), are acute inflammatory vesiculobullous reactions of the skin and mucous membranes, including the ocular surface, oral cavity, and genitals. These reactions are very rare but are often associated with inciting drugs, infectious agents, or both. OBJECTIVE: We sought to identify susceptibility loci for cold...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alternative Splicing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Anti-Inflammatory Agents, Non-Steroidal

Share to Genetic Loci

Share to HLA-A Antigens

Share to Ikaros Transcription Factor

Share to Mouth Mucosa

Share to Protein Isoforms

Share to Stevens-Johnson Syndrome

Source

Open in PubMed

Identifiers

PMID: 25672763
DOI: 10.1016/j.jaci.2014.12.1916

Genes

IKZF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

IKZF1, a new susceptibility gene for cold medicine-related Stevens-Johnson syndrome/toxic epidermal necrolysis with severe mucosal involvement.PMID 25672763Read ↗

Genetic Predisposition to Stevens-Johnson Syndrome With Severe Ocular Surface Complications.Semantic proximity Read ↗

Independent strong association of HLA-A*02:06 and HLA-B*44:03 with cold medicine-related Stevens-Johnson syndrome with severe mucosal involvementSemantic proximity Read ↗

Stevens-Johnson syndrome/toxic epidermal necrolysis with severe ocular complications.Semantic proximity Read ↗

Association of human antigen class I genes with cold medicine-related Stevens-Johnson syndrome with severe ocular complications in a Korean populationSemantic proximity Read ↗

Trans-ethnic study confirmed independent associations of HLA-A*02:06 and HLA-B*44:03 with cold medicine-related Stevens-Johnson syndrome with severe ocular surface complications.Semantic proximity Read ↗

Identification of HLA-A*02:06:01 as the primary disease susceptibility HLA allele in cold medicine-related Stevens-Johnson syndrome with severe ocular complications by high-resolution NGS-based HLA typing.Semantic proximity Read ↗

HLA genotypes and cold medicine-induced Stevens-Johnson syndrome/toxic epidermal necrolysis with severe ocular complications: a systematic review and meta-analysis.Semantic proximity Read ↗

Mucocutaneous inflammation in the Ikaros Family Zinc Finger 1‐keratin 5–specific transgenic miceSemantic proximity Read ↗

Effect of Infectious Diseases on the Pathogenesis of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis.Semantic proximity Read ↗

Human Leukocyte Antigen Class I Genes Associated With Stevens-Johnson Syndrome and Severe Ocular Complications Following Use of Cold Medicine in a Brazilian Population.Semantic proximity Read ↗

Stevens Johnson syndrome: A review of a vision and life-threatening mucocutaneous disease including histopathology with updates on pathogenesis and genetic risk factors.Semantic proximity Read ↗

Association between HLA-B*44:03-HLA-C*07:01 haplotype and cold medicine-related Stevens-Johnson syndrome with severe ocular complications in Thailand.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.