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Article

YAP and the Hippo pathway in pediatric cancer

25 Feb 2017

Abstract excerpt

The Hippo pathway is an important signaling pathway that controls cell proliferation and apoptosis. It is evolutionarily conserved in mammals and is stimulated by cell-cell contact, inhibiting cell proliferation in response to increased cell density. During early embryonic development, the Hippo signaling pathway regulates organ development and size, and its functions result in the coordinated balance between...

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PMID: 28616573
DOI: 10.1080/23723556.2017.1295127

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