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Article

Impaired function of regulatory T-cells in patients with chronic obstructive pulmonary disease (COPD).

Immunobiology - 1 Dec 2014

Tan Dino B A, Fernandez Sonia, Price Patricia, French Martyn A, Thompson Philip J, Moodley Yuben P

Abstract excerpt

Anti-inflammatory pathways affecting chronic obstructive pulmonary disease (COPD) are poorly understood. Regulatory T-cells (Tregs) are important negative regulators of T-cell activity and hence were investigated in COPD patients in this study. We hypothesised that functional defects in Tregs may promote increased inflammation contributing to the pathogenesis of COPD. Peripheral blood mononuclear cells (PBMC)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25097153
DOI: 10.1016/j.imbio.2014.07.005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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