Article
T regulatory cell phenotypes in peripheral blood and bronchoalveolar lavage from non-asthmatic and asthmatic subjects.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Nov 2015
Baatjes A J, Smith S G, Watson R, Howie K, Murphy D, Larché M, Denburg J A, Inman M D, O'Byrne P M
Abstract excerpt
BACKGROUND: An unresolved issue in T regulatory cells' cell biology is the lack of consensus on phenotypic markers that accurately define the natural Treg (nTreg) population. OBJECTIVES: To examine nTreg frequency and functional capacity in healthy controls and their frequency in asthmatic subjects using three different phenotypic strategies. We hypothesized that phenotypically different nTreg are quantitatively...
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