Article
The proportion and function of peripheral myeloid-derived suppressor cells do not correlate with systemic inflammation in chronic obstructive pulmonary disease.
Human immunology - 1 Jan 2014
Tan Dino B A, Fernandez Sonia, Price Patricia, Moodley Yuben P
Abstract excerpt
Myeloid-derived suppressor cells (MDSC) have been implicated in the regulation of chronic inflammation. Chronic obstructive pulmonary disease (COPD) involves persistent inflammation, but the role of MDSC has not been explored. Here, proportions of MDSC (CD14(-)HLA-DR(-)CD33(+)CD11b(+) cells) were quantified in peripheral blood mononuclear cells (PBMC) isolated from patients with 'stable' COPD (n = 12), smokers...
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