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Article

Distinctive Regulatory T Cells and Altered Cytokine Profile Locally in the Airways of Young Smokers with Normal Lung Function.

PloS one - 1 Jan 2016

Ostadkarampour Mahyar, Müller Malin, Öckinger Johan, Kullberg Susanna, Lindén Anders, Eklund Anders, Grunewald Johan, Wahlström Jan

Abstract excerpt

Smoking influences the immune system in different ways and, hypothetically, effects on pulmonary effector and regulatory T cells emerge as potentially detrimental. Therefore, we characterized the frequencies and characteristics of CD4+ and CD8+ T cell subsets in the blood and lungs of young tobacco smokers. Bronchoalveolar lavage (BAL) and peripheral blood were obtained from healthy moderate smokers (n = 18; 2-24...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukocytes, Mononuclear

Share to Pulmonary Disease, Chronic Obstructive

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Identifiers

PMID: 27798682
DOI: 10.1371/journal.pone.0164751
PMCID: PMC5087844

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