Article
Using gene expression to improve the power of genome-wide association analysis.
Human heredity - 1 Jan 2014
Ho Yen-Yi, Baechler Emily C, Ortmann Ward, Behrens Timothy W, Graham Robert R, Bhangale Tushar R, Pan Wei
Abstract excerpt
BACKGROUND/AIMS: Genome-wide association (GWA) studies have reported susceptible regions in the human genome for many common diseases and traits; however, these loci only explain a minority of trait heritability. To boost the power of a GWA study, substantial research endeavors have been focused on integrating other available genomic information in the analysis. Advances in high through-put technologies have...
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