Article
Exploration, normalization, and genotype calls of high-density oligonucleotide SNP array data.
Biostatistics (Oxford, England) - 1 Apr 2007
Carvalho Benilton, Bengtsson Henrik, Speed Terence P, Irizarry Rafael A
Abstract excerpt
In most microarray technologies, a number of critical steps are required to convert raw intensity measurements into the data relied upon by data analysts, biologists, and clinicians. These data manipulations, referred to as preprocessing, can influence the quality of the ultimate measurements. In the last few years, the high-throughput measurement of gene expression is the most popular application of microarray...
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