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Article

Admixture of beneficial and unfavourable variants of GLCCI1 and FCER2 in Roma samples can implicate different clinical response to corticosteroids.

Molecular biology reports - 1 Nov 2014

Szalai Renata, Matyas Petra, Varszegi Dalma, Melegh Marton, Magyari Lili, Jaromi Luca, Sumegi Katalin, Duga Balazs, Kovesdi Erzsebet, Hadzsiev Kinga, Melegh Bela

Abstract excerpt

Variants of glucocorticoid induced transcript 1 (GLCCI1) result decreased response to inhaled corticosteroids, while intronic variant of low-affinity IgE receptor (FCER2) is associated with exacerbation rates in children with asthma. We examined the ethnic differences, allele and genotype frequencies of two linked single nucleotide polymorphisms (rs37972, rs37973) of GLCCI1 and rs28364072 intronic variant of...

Read the complete abstract on PubMed

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Share to Administration, Inhalation
Share to Adrenal Cortex Hormones
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Share to Lectins, C-Type
Share to Receptors, Glucocorticoid
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Source

Identifiers

PMID: 25091946
DOI: 10.1007/s11033-014-3659-7

Genes

GLCCI1
FCER2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Admixture of beneficial and unfavourable variants of GLCCI1 and FCER2 in Roma samples can implicate different clinical response to corticosteroids.PMID 25091946Read ↗

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