Article
Impact of the genetic variants of GLCCI1 on clinical features of asthmatic patients.
The clinical respiratory journal - 1 Mar 2018
Chiba Shinji, Nakamura Yutaka, Mizuno Tomoki, Abe Kazuyuki, Horii Yosuke, Nagashima Hiromi, Sasaki Nobuhito, Kanno Hiroyuki, Tanita Tatsuo, Yamauchi Kohei
Abstract excerpt
BACKGROUND: Several gene variants are associated with a response to an inhaled corticosteroids (ICSs) treatment in patients with bronchial asthma. A variant of the glucocorticoid-induced transcript 1 (GLCCI1) genes has previously been associated with decreased lung function improvement upon treatment with ICSs in patients with bronchial asthma. Another report has also demonstrated that this genetic biomarker did...
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