Article
GLCCI1 rs37973: A potential genetic predictor of therapeutic response to inhaled corticosteroids in Chinese asthma patients.
Medicine - 1 Dec 2017
Xu Yuzhu, Wu Hongxu, Wu Xiaojie, Xu Yongjian, Zhao Jianping, Xie Jungang, Yu Jun
Abstract excerpt
Glucocorticoids are the primary anti-inflammatory therapy for asthma, but their effects are characterized by some interindividual variability that might have a genetic basis.We aimed to determine the relationship between pulmonary function change and the variant of the glucocorticoid-induced transcript 1 (GLCCI1) gene in patients with asthma receiving long-term ICS treatment, the association of GLCCI1 genotypes...
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