Article
GLCCI1 gene body methylation in peripheral blood is associated with asthma and asthma severity.
Clinica chimica acta; international journal of clinical chemistry - 1 Dec 2021
Jiang Yuanyuan, Xun Qiufen, Wan Rongjun, Deng Shuanglinzi, Hu Xinyue, Luo Lisha, Li Xiaozhao, Feng Juntao
Abstract excerpt
BACKGROUND AND AIMS: Epigenetic changes play a role in the occurrence of asthma. In this study, we evaluated the methylation status of glucocorticoid-induced transcript 1 (GLCCI1) and assessed its associations with asthma and asthma severity. MATERIALS AND METHODS: Peripheral blood mononuclear cells were harvested from 33 severe asthma patients, 84 mild-moderate asthma patients and 79 healthy controls of Han...
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