Article
GLCCI1 rs37973: a potential genetic predictor of therapeutic response to inhaled corticosteroids in Chinese chronic obstructive pulmonary disease patients.
Scientific reports - 10 Feb 2017
Lei Yuan, Gao Yiping, Chen Jinkun, Li Miao, Wu Xiaomei, Ning Qin, Zhao Jianping, Xiong Weining, Xu Yongjian, Xie Jungang
Abstract excerpt
Inhaled corticosteroids (ICSs) are widely prescribed in chronic obstructive pulmonary disease (COPD). However, little is known about predictors of ICSs therapeutic response. To investigate whether the variation in glucocorticoid-induced transcript 1 (GLCCI1) rs37973 is associated with ICS efficacy. A total of 204 clinically stable COPD patients were recruited and administered to inhaled fluticasone...
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