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Article

A farnesoid X receptor polymorphism predisposes to spontaneous bacterial peritonitis.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver - 1 Nov 2014

Lutz Philipp, Berger Cordula, Langhans Bettina, Grünhage Frank, Appenrodt Beate, Nattermann Jacob, Lammert Frank, Hoerauf Achim, Sauerbruch Tilman, Strassburg Christian P, Spengler Ulrich, Nischalke Hans Dieter

Abstract excerpt

BACKGROUND: In mice, the farnesoid X receptor is involved in bacterial translocation, which can result in spontaneous bacterial peritonitis in patients with cirrhosis. We investigated if polymorphisms in the farnesoid X receptor gene influence the risk for spontaneous bacterial peritonitis. METHODS: Laboratory and clinical data of 293 cirrhotic patients with ascites and 226 healthy controls were prospectively...

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Identifiers

PMID: 25086996
DOI: 10.1016/j.dld.2014.07.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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