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Article

CC-type chemokine receptor 5-Delta32 mutation protects against primary sclerosing cholangitis.

Inflammatory bowel diseases - 1 Apr 2006

Henckaerts Liesbet, Fevery Johan, Van Steenbergen Werner, Verslype Chris, Yap Paul, Nevens Frederik, Roskams Tania, Libbrecht Louis, Rutgeerts Paul, Vermeire Séverine

Abstract excerpt

BACKGROUND: Primary sclerosing cholangitis (PSC) is commonly associated with inflammatory bowel disease (IBD) and characterized by fibrosing inflammatory destruction of biliary ducts. The pathogenesis of PSC remains unknown, but immunological, bacterial, viral, and toxic factors play a role in a genetically susceptible host. We hypothesized that CC-type chemokine receptor 5 (CCR5) would be an interesting...

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Identifiers

PMID: 16633049
DOI: 10.1097/01.MIB.0000209790.21737.28

Genes

CCR5

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CC-type chemokine receptor 5-Delta32 mutation protects against primary sclerosing cholangitis.PMID 16633049Read ↗

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