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RAD51C germline mutations found in Spanish site-specific breast cancer and breast-ovarian cancer families.

Breast cancer research and treatment - 1 Aug 2014

Blanco Ana, Gutiérrez-Enríquez Sara, Santamariña Marta, Montalban Gemma, Bonache Sandra, Balmaña Judith, Carracedo Angel, Diez Orland, Vega Ana

Abstract excerpt

BRCA1 and BRCA2 are the most well-known breast and ovarian cancer susceptibility genes. Additional genes involved in DNA repair have been identified as predisposing to breast cancer. Recently, RAD51C, a new Fanconi Anemia gene, essential for homologous recombination repair, has been reported to be a rare hereditary breast and ovarian cancer susceptibility gene. Indeed, several pathogenic mutations have been...

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Identifiers

PMID: 25086635
DOI: 10.1007/s10549-014-3078-4

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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RAD51C germline mutations found in Spanish site-specific breast cancer and breast-ovarian cancer families.PMID 25086635Read ↗

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RAD51C is a susceptibility gene for ovarian cancer.Semantic proximity Read ↗

Further evidence for the contribution of the RAD51C gene in hereditary breast and ovarian cancer susceptibility.Semantic proximity Read ↗

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Germline mutation in the RAD51B gene confers predisposition to breast cancer.Semantic proximity Read ↗

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