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RAD51C is a susceptibility gene for ovarian cancer.

Human molecular genetics - 15 Aug 2011

Pelttari Liisa M, Heikkinen Tuomas, Thompson Deborah, Kallioniemi Anne, Schleutker Johanna, Holli Kaija, Blomqvist Carl, Aittomäki Kristiina, Bützow Ralf, Nevanlinna Heli

Abstract excerpt

A homozygous mutation in the RAD51C gene was recently found to cause Fanconi anemia-like disorder. Furthermore, six heterozygous deleterious RAD51C mutations were detected in German breast and ovarian cancer families. We screened 277 Finnish familial breast or ovarian cancer patients for RAD51C and identified two recurrent deleterious mutations (c.93delG and c.837+1G>A). These mutations were further genotyped in...

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Identifiers

PMID: 21616938
DOI: 10.1093/hmg/ddr229

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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RAD51C is a susceptibility gene for ovarian cancer.PMID 21616938Read ↗

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