Article
Gene set enrichment analysis for multiple continuous phenotypes.
BMC bioinformatics - 3 Aug 2014
Wang Xiaoming, Pyne Saumyadipta, Dinu Irina
Abstract excerpt
BACKGROUND: Gene set analysis (GSA) methods test the association of sets of genes with phenotypes in gene expression microarray studies. While GSA methods on a single binary or categorical phenotype abounds, little attention has been paid to the case of a continuous phenotype, and there is no method to accommodate correlated multiple continuous phenotypes. RESULT: We propose here an extension of the linear...
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