Article
A comparative study on gene-set analysis methods for assessing differential expression associated with the survival phenotype.
BMC bioinformatics - 26 Sept 2011
Lee Seungyeoun, Kim Jinheum, Lee Sunho
Abstract excerpt
BACKGROUND: Many gene-set analysis methods have been previously proposed and compared through simulation studies and analysis of real datasets for binary phenotypes. We focused on the survival phenotype and compared the performances of Gene Set Enrichment Analysis (GSEA), Global Test (GT), Wald-type Test (WT) and Global Boost Test (GBST) methods in a simulation study and on two ovarian cancer data sets. We...
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