Unite and conquer: univariate and multivariate approaches for finding differentially expressed gene sets.

Abstract excerpt

MOTIVATION: Recently, many univariate and several multivariate approaches have been suggested for testing differential expression of gene sets between different phenotypes. However, despite a wealth of literature studying their performance on simulated and real biological data, still there is a need to quantify their relative performance when they are testing different null hypotheses. RESULTS: In this article,...

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