Article
Gene interaction enrichment and network analysis to identify dysregulated pathways and their interactions in complex diseases.
BMC systems biology - 13 Jun 2012
Liu Yu, Koyutürk Mehmet, Barnholtz-Sloan Jill S, Chance Mark R
Abstract excerpt
BACKGROUND: The molecular behavior of biological systems can be described in terms of three fundamental components: (i) the physical entities, (ii) the interactions among these entities, and (iii) the dynamics of these entities and interactions. The mechanisms that drive complex disease can be pr...
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