Article
Up-regulation of urinary-type plasminogen activator correlates with high-risk papillary thyroid carcinoma with BRAF(V600E) mutation and its possible molecular mechanism.
Pathology, research and practice - 1 Nov 2014
Wakasa Tomoko, Li Yaqiong, Bai Yanhua, Liu Zhiyan, Ozaki Takashi, Mori Ichiro, Miyauchi Akira, Kakudo Kennichi, Nakamura Misa
Abstract excerpt
The aim of the present study is to investigate the relationship between urinary-type plasminogen activator (uPA) expression and clinicopathological features in papillary thyroid carcinoma (PTC) and to determine the signal transduction of PTC cells in vitro. PTC tissues from 42 patients were analyzed for the expression of uPA and the BRAF(V600E) mutation. BCPAP, a PTC cell line harboring the BRAF(V600E) mutation,...
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