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Article

Relationships of BRAF mutation and HMGB1 to papillary thyroid carcinoma.

Biochemical and biophysical research communications - 13 May 2017

Guan Xiaolei, Wang Ping, Chi Jingwei, Zhao Shihua, Wang Fei

Abstract excerpt

A poor papillary thyroid cancer (PTC) prognosis is strongly associated with the BRAF V600E mutation. During tumor progression, levels of the high mobility group box 1 (HMGB1) protein are often dysregulated. Results herein demonstrate that HMGB1 protein levels differ between tumor and adjacent non-tumor tissue and that HMGB1 mRNA levels were higher in wild-type BRAF PTC tissues than in BRAF V600E PTC tissues...

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Topics

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Share to Carcinoma
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Proto-Oncogene Proteins B-raf

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Source

Identifiers

PMID: 28342873
DOI: 10.1016/j.bbrc.2017.03.117

Genes

BRAF
HMGB1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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