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Article

Expression of the plasminogen activation system in kidney cancer correlates with its aggressive phenotype.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Apr 1998

Swiercz R, Wolfe J D, Zaher A, Jankun J

Abstract excerpt

Malignant tumors contrast with benign ones in their ability to invade adjacent tissue and to metastasize. The urokinase plasminogen activator is a proteolytic enzyme that can facilitate these processes. In many carcinomas, the concentration of the urokinase plasminogen activator system is high. The high expression of these enzymes is related to tumor grade. In this study, we have investigated whether secretion of...

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PMID: 9563880

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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