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Article

The effects of urokinase-type plasminogen activator (uPA) on cell proliferation and phenotypic transformation of rat mesangial cells induced by high glucose.

Diabetes research and clinical practice - 1 Mar 2014

Cheng Hui, Chen Cheng, Wang Siyuan, Ding Guohua, Shi Ming

Abstract excerpt

AIMS: To investigate the effects of urokinase-type plasminogen activator (uPA) on proliferation and phenotypic transformation of rat mesangial cells (MCs) under high glucose conditions and its possible signal transduction pathway. METHODS: Rat MC were divided into 4 groups: the control group, the high glucose group, the high glucose and wortmannin group, and the high glucose and uPA group. MC proliferation in all...

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Source

Identifiers

PMID: 24447806
DOI: 10.1016/j.diabres.2013.11.016

Genes

CDK2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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