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Article

Characterization of genomic single nucleotide polymorphism via colorimetric detection using a single gold nanoprobe.

Analytical biochemistry - 15 Nov 2014

Carlos Fábio Ferreira, Flores Orfeu, Doria Gonçalo, Baptista Pedro Viana

Abstract excerpt

Identification of specific nucleic acid sequences mediated by gold nanoparticles derivatized thiol-modified oligonucleotides (Au-nanoprobes) has been proven to be a useful tool in molecular diagnostics. Here, we demonstrate that, on optimization, detection may be simplified via the use of a single Au-nanoprobe to detect a single nucleotide polymorphism (SNP) in homo- or heterozygote condition. We validated this...

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PMID: 25077987
DOI: 10.1016/j.ab.2014.07.019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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