Single nucleotide polymorphism detection using gold nanoprobes and bio-microfluidic platform with embedded microlenses.

doi:10.1002/bit.25542

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Article

Single nucleotide polymorphism detection using gold nanoprobes and bio-microfluidic platform with embedded microlenses.

Biotechnology and bioengineering - 1 Jun 2015

Bernacka-Wojcik Iwona, Águas Hugo, Carlos Fabio Ferreira, Lopes Paulo, Wojcik Pawel Jerzy, Costa Mafalda Nascimento, Veigas Bruno, Igreja Rui, Fortunato Elvira, Baptista Pedro Viana, Martins Rodrigo

Abstract excerpt

The use of microfluidics platforms combined with the optimal optical properties of gold nanoparticles has found plenty of application in molecular biosensing. This paper describes a bio-microfluidic platform coupled to a non-cross-linking colorimetric gold nanoprobe assay to detect a single nucleotide polymorphism associated with increased risk of obesity fat-mass and obesity-associated (FTO) rs9939609 (Carlos et...

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PMID: 25765286
DOI: 10.1002/bit.25542

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