Colorimetric genotyping of single nucleotide polymorphism based on selective aggregation of unmodified gold nanoparticles.

doi:10.1016/j.bios.2010.06.050

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Article

Colorimetric genotyping of single nucleotide polymorphism based on selective aggregation of unmodified gold nanoparticles.

Biosensors & bioelectronics - 15 Oct 2010

Lee Hosub, Joo Sang-Woo, Lee So Yeong, Lee Chang-Ha, Yoon Kyong-Ah, Lee Kangtaek

Abstract excerpt

We have developed a colorimetric method for genotyping of single nucleotide polymorphism (rs2131877) in 15 human DNA samples using selective aggregation of unmodified gold nanoparticles. First, we designed two different types of oligonucleotide probes with either thymine or cytosine at the end that are perfect complementary to the target allele sequence. After hybridization of the probe and target DNAs, the...

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PMID: 20674325
DOI: 10.1016/j.bios.2010.06.050

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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