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Article

A genotyping method for VKORC1 1173C > T by Pyrosequencing technology.

Scandinavian journal of clinical and laboratory investigation - 1 Jan 2008

Enström Camilla, Osman Abdimajid, Lindahl Tomas L

Abstract excerpt

Vitamin K epoxide reductase complex subunit 1 (VKORC1) is the site of inhibition by warfarin and other antivitamin K drugs during oral anticoagulant therapy. The SNP rs9934438 in intron 1 of VKORC1 (c.173+1000C > T or 1173C > T) discriminating the VKORC1*2 haplotype is associated with low warfarin dose requirement and unstable prothrombin time - international normalized ratio. To genotype this SNP, we have...

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Source

Identifiers

PMID: 19172700
DOI: 10.1080/00365510701810621

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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