Article
Comparisons of CYP2C19 genetic polymorphisms between Korean and Vietnamese populations.
Therapeutic drug monitoring - 1 Aug 2007
Lee Sang Seop, Lee Su-Jun, Gwak Jungsug, Jung Hyun-Ju, Thi-Le Houng, Song Im-Sook, Kim Eun-Young, Shin Jae-Gook
Abstract excerpt
It is well known that CYP2C19 is an enzyme showing genetic polymorphism that may cause marked interindividual and interethnic variation in the metabolism and disposition of its substrates. This study compared the frequency distribution of CYP2C19*1, *2, and *3 alleles in Korean and Vietnamese populations, representing Far Eastern and Southwestern Asian populations, respectively. The presence of the CYP2C19...
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