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Article

Association between seven single nucleotide polymorphisms involved in inflammation and proteolysis and abdominal aortic aneurysm.

Journal of vascular surgery - 1 May 2015

Saratzis Athanasios, Bown Matthew J, Wild Ben, Nightingale Peter, Smith Jacqueline, Johnson Christopher, Melas Nikolaos, Kitas George D

Abstract excerpt

BACKGROUND: Abdominal aortic aneurysm (AAA) formation involves an inflammatory and proteolytic process. Previous studies suggest that AAA is a multifactorial disease with a strong genetic background. This study evaluated the role of seven important functional single nucleotide polymorphisms (SNPs) in AAA. METHODS: This was a case-control study of two independent populations: 397 AAA patients (mean aortic...

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Source

Identifiers

PMID: 24613192
DOI: 10.1016/j.jvs.2013.11.099

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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