Article
A matrilineal genetic legacy from the last glacial maximum confers susceptibility to schizophrenia in Han Chinese.
Journal of genetics and genomics = Yi chuan xue bao - 20 Jul 2014
Zhang Wen, Tang Jinsong, Zhang A-Mei, Peng Min-Sheng, Xie Hai-Bing, Tan Liwen, Xu Lin, Zhang Ya-Ping, Chen Xiaogang, Yao Yong-Gang
Abstract excerpt
Mitochondrial dysfunction has been widely reported in schizophrenia patients. To dissect the matrilineal structure of Han Chinese with or without schizophrenia and to decipher the maternal influence and evolutionary history of schizophrenia, a total of 1212 schizophrenia patients and 1005 matched healthy controls, all of Han Chinese origin, were recruited in Hunan Province, China. We classified haplogroup for...
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