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Article

Resolving the effects of maternal and offspring genotype on dyadic outcomes in genome wide complex trait analysis ("M-GCTA").

Behavior genetics - 1 Sept 2014

Eaves Lindon J, Pourcain Beate St, Smith George Davey, York Timothy P, Evans David M

Abstract excerpt

Genome wide complex trait analysis (GCTA) is extended to include environmental effects of the maternal genotype on offspring phenotype ("maternal effects", M-GCTA). The model includes parameters for the direct effects of the offspring genotype, maternal effects and the covariance between direct and maternal effects. Analysis of simulated data, conducted in OpenMx, confirmed that model parameters could be...

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Identifiers

PMID: 25060210
DOI: 10.1007/s10519-014-9666-6
PMCID: PMC4174369

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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