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Article

Innovative approach to identify multigenomic and environmental interactions associated with birth defects in family-based hybrid designs.

Genetic epidemiology - 1 Mar 2021

Lou Xiang-Yang, Hou Ting-Ting, Liu Shou-Ye, Xu Hai-Ming, Lin Feng, Tang Xinyu, MacLeod Stewart L, Cleves Mario A, Hobbs Charlotte A

Abstract excerpt

Genes, including those with transgenerational effects, work in concert with behavioral, environmental, and social factors via complex biological networks to determine human health. Understanding complex relationships between causal factors underlying human health is an essential step towards deciphering biological mechanisms. We propose a new analytical framework to investigate the interactions between maternal...

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PMID: 32996630
DOI: 10.1002/gepi.22363
PMCID: PMC8495752

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