Article
Genetic association between a 'standing' variant of NOD2 and bipolar disorder.
Immunobiology - 1 Oct 2014
Oliveira José, Hamdani Nora, Etain Bruno, Bennabi Meriem, Boukouaci Wahid, Amokrane Kahina, Fortier Catherine, Marzais François, Bengoufa Djaouida, Bellivier Frank, Henry Chantal, Kahn Jean-Pierre, Charron Dominique, Krishnamoorthy Rajagopal, Leboyer Marion, Tamouza Ryad
Abstract excerpt
Bipolar disorders (BD) are chronic, multisystem and multifactorial disorders with significant lifetime morbidity, mortality and socio-economic burden. Understanding the underlying genetic and disease triggering environmental factors should improve diagnosis, prognosis, prevention and therapeutic management of the disease. Since intestinal innate dysimmunity seems to play a significant role in the etiopathogeny of...
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