Article
Association between nucleotide oligomerisation domain two (Nod2) gene polymorphisms and canine inflammatory bowel disease.
Veterinary immunology and immunopathology - 15 Sept 2014
Kathrani A, Lee H, White C, Catchpole B, Murphy A, German A, Werling D, Allenspach K
Abstract excerpt
The most important genetic associations that have been implicated to play a role in the etiology of Crohn's disease (CD) in humans are single nucleotide polymorphisms (SNPs) in nucleotide oligomerisation domain 2 (NOD2). The aim of this study was to investigate whether SNPs in the canine NOD2 gene are associated with inflammatory bowel disease (IBD) in German shepherd dogs (GSDs) and other canine breeds. A...
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