Article
NOD2: ethnic and geographic differences.
World journal of gastroenterology - 21 Jun 2006
Cavanaugh Juleen
Abstract excerpt
Investigations into the inheritance of the three risk alleles R702W, G908R and 1007fsInsC in NOD2 associated with susceptibility to Crohn's disease have demonstrated a remarkable amount of heterogeneity across ethnicities and populations, with regional variation across Europe for example, suggesting local founder effects. In non-Caucasian populations Crohn's disease continues to increase in incidence but this...
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