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Article

The mutational burdens and evolutionary ages of early gastric cancers are comparable to those of advanced gastric cancers.

The Journal of pathology - 1 Nov 2014

Kim Tae-Min, Jung Seung-Hyun, Kim Min Sung, Baek In-Pyo, Park Sung-Won, Lee Sung Hak, Lee Han Hong, Kim Sung Soo, Chung Yeun-Jun, Lee Sug Hyung

Abstract excerpt

Early gastric cancers (EGCs) precede advanced gastric cancers (AGCs), with a favourable prognosis compared to AGC. To understand the progression mechanism of EGC to AGC, it is required to disclose EGC and AGC genomes in mutational and evolutionary perspectives. We performed whole-exome sequencing and copy number profiling of nine microsatellite (MS)-unstable (MSI-H) (five EGCs and four AGCs) and eight MS-stable...

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PMID: 25042771
DOI: 10.1002/path.4401

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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