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Article

Molecular features of early- vs. late-onset gastric cancer: a systematic review and meta-analysis.

BMC cancer - 14 Jan 2026

Lin Xinmei, Shi Wenhan, Zhou Zitong, Li Degang, Yao Qiuyuan, Sun Yu

Abstract excerpt

BACKGROUND: Early-onset gastric cancer (EOGC), diagnosed before age 50, is characterized by distinct clinicopathological features, though its molecular landscape remains poorly defined. METHODS: A systematic literature search of PubMed, Embase, and Web of Science identified studies comparing molecular characteristics of EOGC and late-onset gastric cancer (LOGC). Meta-analyses assessed differences in The Cancer...

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Identifiers

PMID: 41535782
DOI: 10.1186/s12885-026-15567-5
PMCID: PMC12888746

Genes

CDH1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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