Molecular features of early- vs. late-onset gastric cancer: a systematic review and meta-analysis

Abstract excerpt

<title>Abstract</title> <p> <bold>Background:</bold> Early-onset gastric cancer (EOGC), diagnosed before the age of 50, exhibits distinct clinicopathological and molecular characteristics compared to late-onset gastric cancer (LOGC). However, the molecular landscape of EOGC remains incompletely defined. This study systematically reviews and meta-analyzes the molecular differences between EOGC and LOGC. <bold>M...

Topics

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• Age of Onset
• Biomarkers, Tumor
• Chromosomal Instability
• Epigenesis, Genetic
• Gene Expression Regulation, Neoplastic
• Mutation
• Odds Ratio
• Stomach Neoplasms

Identifiers and source

Literature Corpus work

bd80f972-7d86-581f-97a5-d9676f5ebf8d

DOI

10.21203/rs.3.rs-6435874/v1