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Article

A systematic study of single-nucleotide polymorphisms in the A4GALT gene suggests a molecular genetic basis for the P1/P2 blood groups.

Transfusion - 1 Dec 2014

Lai Yin-Ju, Wu Wan-Yi, Yang Chen-Ming, Yang Li-Rong, Chu Chen-Chung, Chan Yung-Syu, Lin Marie, Yu Lung-Chih

Abstract excerpt

BACKGROUND: The molecular mechanism for the formation of the P1/P2 blood groups remains unsolved. It has been shown that the P1/P2 polymorphism is connected to the different A4GALT gene expression levels in P1 and P2 red blood cells. STUDY DESIGN AND METHODS: The present investigation conducted a pilot investigation that involved the detailed and stepwise screening of single-nucleotide polymorphisms (SNPs) in the...

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PMID: 25041587
DOI: 10.1111/trf.12771

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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