Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The differential expression of the blood group P1 -A4GALT and P2 -A4GALT alleles is stimulated by the transcription factor early growth response 1.

Transfusion - 1 Apr 2018

Yeh Chih-Chun, Chang Ching-Jin, Twu Yuh-Ching, Hung Shu-Ting, Tsai Yi-Jui, Liao Jia-Ching, Huang Ji-Ting, Kao Yu-Hsin, Lin Sheng-Wei, Yu Lung-Chih

Abstract excerpt

BACKGROUND: The P1 /P2 phenotypic polymorphism is one of the earliest blood groups discovered in humans. These blood groups have been connected to different levels of expression of the A4GALT gene in P1 and P2 red blood cells; however, the detailed molecular genetic mechanism that leads to these two phenotypes has not been established. STUDY DESIGN AND METHODS: After our previous identification of an association...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Computer Simulation
Share to Early Growth Response Protein 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Electrophoretic Mobility Shift Assay

Share to Galactosyltransferases

Share to Genes, Reporter

Share to HEK293 Cells

Share to Recombinant Proteins

Share to Transcription, Genetic

Source

Identifiers

PMID: 29399809
DOI: 10.1111/trf.14515

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The differential expression of the blood group P1 -A4GALT and P2 -A4GALT alleles is stimulated by the transcription factor early growth response 1.PMID 29399809Read ↗

A systematic study of single-nucleotide polymorphisms in the A4GALT gene suggests a molecular genetic basis for the P1/P2 blood groups.Semantic proximity Read ↗

Allele-selective RUNX1 binding regulates P1 blood group status by transcriptional control of A4GALT.Semantic proximity Read ↗

Identification of a novel A4GALT exon reveals the genetic basis of the P1/P2 histo-blood groups.Semantic proximity Read ↗

The P1PK blood group system: revisited and resolved.Semantic proximity Read ↗

Two previously proposed P1/P2-differentiating and nine novel polymorphisms at the A4GALT (Pk) locus do not correlate with the presence of the P1 blood group antigen.Semantic proximity Read ↗

Human Histo-blood Group ABO Glycosyltransferase Genes: Different Enhancer Structures with Different Transcriptional ActivitiesSemantic proximity Read ↗

The molecular genetic background leading to the formation of the human erythroid-specific Xga/CD99 blood groups.Semantic proximity Read ↗

Blood group P1 prediction using multiplex PCR genotyping of A4GALT among Thai blood donors.Semantic proximity Read ↗

P1PK, GLOB, and FORS blood group systems and GLOB collection: biochemical and clinical aspects. Do we understand it all yet?Semantic proximity Read ↗

Single nucleotide polymorphisms in A4GALT spur extra products of the human Gb3/CD77 synthase and underlie the P1PK blood group system.Semantic proximity Read ↗

Biological and clinical significance of haptoglobin polymorphism in humansSemantic proximity Read ↗

Novel A4GALT Variants Cause Rare p Phenotype and Recurrent Pregnancy Loss in a Chinese Individual.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.