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Article

Identification of a novel A4GALT exon reveals the genetic basis of the P1/P2 histo-blood groups.

Blood - 13 Jan 2011

Thuresson Britt, Westman Julia S, Olsson Martin L

Abstract excerpt

The A4GALT locus encodes a glycosyltransferase that synthesizes the terminal Galα1-4Gal of the P(k) (Gb3/CD77) glycosphingolipid, important in transfusion medicine, obstetrics, and pathogen susceptibility. Critical nucleotide changes in A4GALT not only abolish P(k) formation but also another Galα1-4Gal-defined antigen, P1, which belongs to the only blood group system for which the responsible locus remains...

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Source

Identifiers

PMID: 20971946
DOI: 10.1182/blood-2010-08-301333

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Identification of a novel A4GALT exon reveals the genetic basis of the P1/P2 histo-blood groups.PMID 20971946Read ↗

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