Article
Blood group P1 prediction using multiplex PCR genotyping of A4GALT among Thai blood donors.
Transfusion medicine (Oxford, England) - 1 Feb 2021
Thinley Jigme, Nathalang Oytip, Chidtrakoon Sarisa, Intharanut Kamphon
Abstract excerpt
OBJECTIVES: This study aimed to investigate single-nucleotide variants (SNVs) associated with P1 expression among Thai blood donors and develop a genotyping method using multiplex polymerase chain reaction (PCR) to predict P1 blood group status. BACKGROUND: The α1,4-galactosyltransferase (A4GALT), also called Gb3/CD77 synthase or P1/Pk synthase enzyme, is encoded by the A4GALT gene and catalyses the transfer of...
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