Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Region-specific regulation of the serotonin 2A receptor expression in development and ageing in post mortem human brain.

Neuropathology and applied neurobiology - 1 Jun 2015

Marinova Zoya, Monoranu Camelia-Maria, Fetz Sonja, Walitza Susanne, Grünblatt Edna

Abstract excerpt

AIMS: The serotonin 2A receptor (HTR2A) is widely expressed in the brain and involved in the modulation of fear, mood, anxiety and other symptoms. HTR2A and HTR2A gene variations are implicated in depression, schizophrenia, anxiety and obsessive-compulsive disorder. To understand HTR2A signalling changes in psychiatric or neurodegenerative disorders, its normal pattern of brain expression and region specificity...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to Brain
Share to Child, Preschool

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fetal Development

Share to Infant

Share to Infant, Newborn

Share to Receptor, Serotonin, 5-HT2A

Share to RNA, Messenger

Source

Identifiers

PMID: 25041420
DOI: 10.1111/nan.12167

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Region-specific regulation of the serotonin 2A receptor expression in development and ageing in post mortem human brain.PMID 25041420Read ↗

The Developmental Basis of Epigenetic Regulation of HTR2A and Psychiatric OutcomesSemantic proximity Read ↗

Genetic variation in cortico-amygdala serotonin function and risk for stress-related disease.Semantic proximity Read ↗

Multiple regulatory variants modulate expression of 5-hydroxytryptamine 2A receptors in human cortex.Semantic proximity Read ↗

Genes within the serotonergic system are differentially expressed in human brain.Semantic proximity Read ↗

HTR2A: Association and expression studies in neuropsychiatric geneticsSemantic proximity Read ↗

A unique gene expression signature associated with serotonin 2C receptor RNA editing in the prefrontal cortex and altered in suicideSemantic proximity Read ↗

Epigenetic dysregulation of HTR2A in the brain of patients with schizophrenia and bipolar disorder.Semantic proximity Read ↗

Serotonin receptor 2C and mental disorders: genetic, expression and RNA editing studies.Semantic proximity Read ↗

Early localization of mRNA coding for 5-HT1A receptors in human brain during developmentSemantic proximity Read ↗

Transcriptional regulation at a HTR1A polymorphism associated with mental illness.Semantic proximity Read ↗

Genetically driven variation in serotonin uptake: is there a link to affective spectrum, neurodevelopmental, and neurodegenerative disorders?Semantic proximity Read ↗

Functional interrogation of a depression-related serotonergic SNP, rs6295, using a humanized mouse modelSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.