Article
Genetically driven variation in serotonin uptake: is there a link to affective spectrum, neurodevelopmental, and neurodegenerative disorders?
Biological psychiatry - 1 Aug 1998
Lesch K P, Mössner R
Abstract excerpt
Serotonin (5-HT) is an important regulator of morphogenetic activities during early central nervous system development, including cell proliferation, migration, and differentiation. The 5-HT transporter (5-HTT) plays a pivotal role in brain 5-HT homeostasis. It is also the initial target for both...
Topics
- Adult
- Aged
- Alcoholism
- Animals
- Brain
- Carrier Proteins
- Dementia
- Female
- Gene Expression
- Genetic Variation
- Humans
- Infant, Newborn
- Male
- Membrane Glycoproteins
- Membrane Transport Proteins
- Mood Disorders
- Nerve Degeneration
- Nerve Tissue Proteins