Article
Mannose-Binding Lectin (MBL) and MBL-associated serine protease-2 (MASP-2) in women with malignant and benign ovarian tumours.
Cancer immunology, immunotherapy : CII - 1 Nov 2014
Swierzko Anna St, Szala Agnieszka, Sawicki Sambor, Szemraj Janusz, Sniadecki Marcin, Sokolowska Anna, Kaluzynski Andrzej, Wydra Dariusz, Cedzynski Maciej
Abstract excerpt
Mannose-Binding Lectin (MBL) is a serum pattern recognition molecule, able to activate complement in association with MASP proteases. Serum levels of MBL and MASP-2, activities of MBL-MASP complexes, single nucleotide polymorphisms of the MBL2 and MASP2 genes and/or their specific mRNA expression in ovarian sections were investigated in 128 patients suffering from primary ovarian cancer (OC) and compared with 197...
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